Scientist Bioscience

Description

Duration: 6 months maternity leave contract, extension is unlikely Start date can be moved to end of September if selected candidate is available to start earlier. Location: 100% onsite in Waltham Schedule: Regular business hrs Scientist/Senior Scientist – Small Molecule Drug Discovery Hematology R&D, Waltham, MA Join AstraZeneca’s Oncology Bioscience team in Waltham, MA, and be part of an exciting effort to discover breakthrough therapies in hematology oncology. As a Scientist or Senior Scientist, you’ll drive impactful research by identifying and validating novel targets, designing advanced cell-based assays, and uncovering drug mechanisms that could transform patient outcomes. This is a unique opportunity to innovate at the forefront of oncology drug discovery and accelerate promising therapies from the lab to the clinic, in a highly collaborative, cross-disciplinary environment. Key Responsibilities • Design and execute in vitro studies supporting the characterization and development of oncology drug candidates • Develop, optimize, and troubleshoot cell-based assays (e.g., proliferation, survival, cell cycle, apoptosis) in multiple formats • Support target identification and validation efforts in haematology oncology • Conduct CRISPR screens and validate genetic hits to advance target discovery • Profile compounds and investigate mechanisms of action using state-of-the-art cellular and molecular techniques • Collaborate across disciplines, analyze data, and present results to project teams Qualifications • Ph.D. in cancer biology, cell biology, or a related field with 2+ years’ relevant experience; or Bachelor’s/Master’s with 5+ years’ experience • Hands-on experience with cell culture, CRISPR, western blotting, flow cytometry, qPCR, and phenotypic assays • Strong analytical and communication skills, team orientation, and a proactive, problem-solving approach • Industry experience and familiarity with drug discovery platforms are a plus Take the next step in your career and help shape the future of oncology therapies with AstraZeneca. Interviewing: 1 screen interview folllowed by one onsite panel interview and tour.